The lack of access to accurate and comprehensive sexual health education in the United States continues to be a pressing public health issue. The Sex Wrap (TSW) is a multimedia sexual health podcast and social media presence that educates its followers on sexual health and ancillary themes including sexuality, relationships, and communication. TSW's Instagram account revamps the evidence-based sexual health information from the podcast as original or reposted content. With internet memes becoming a driving cultural force among young adults aged 14-29, the podcast utilizes its Instagram social media presence to effectively stage online health-based social marketing. Comedic value aside, the highly accessible nature of memes makes them a powerful tool for information dissemination. The meme-based sexual health intervention via TSW's Instagram increased engagement, improved reach, and converted followers to podcast listeners. The insight data also demonstrated how employing social media can be used to address disparities in sexual health education caused by the failure of the abstinence-only-until-marriage curricula. This case study demonstrates how social-media based interventions can be used to fill social and legislative gaps in sex education in a comprehensive way.