Prospective and Retrospective Research Study for Covid-19/SARS-CoV2 in vulnerable populations and in Patients with Liver Diseases in South Florida

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Abstract

In December 2019, severe cases of viral pneumonia associated with human-animal interactions were found by the Wuhan Municipal Health Commission. The main forms of transmission were respiratory droplets and close human contact. It was later determined to be severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) through genetic sequencing of microorganism cultures. The main objective of this study was to discover the prevalence of Covid-19 in individuals with and without risk factors. Also focusing on the presence of antibodies to determine its effects on transmission. These risk factors include: occupational exposure, 65 years and older, and underlying health conditions. 

    Two types of Covid-19 tests were performed on each patient. The first type was Total Ab exams to detect IgG and IgM antibodies against SARS-CoV2. The third being the Reverse Transmission Polymerase Chain Reaction (RT-PCR) Test to determine if Covid-19 was present during time of testing. All tests were performed via nasopharyngeal swab by deeply inserting and gently rubbing the swab for several seconds to absorb secretions, and then retrieving. The data collected at the Schiff Center for Liver Diseases in the years 2020-2021 shows that SARS-CoV2 prevailed mostly in individuals without antibodies. Amongst all positive RT-PCR results, no strong correlation was found between those with and without risk factors.

Submission ID :
RCIF43
Submission Type
Research Discipline
Mentor Title :
Dr.
Mentor First Name :
Eugene
Mentor Last Name :
Schiff
Mentor Department :
Miller School of Medicine
Miller School of Medicine Department :
Schiff Center for Liver Diseases

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